The agreement was signed on November 22, 2006, was submitted to the Colombian Congress by President Álvaro Uribe on November 30, 2006. The Bill was debated and voted in a joint session on April 25, 2007. The House Floor approved it on June 5, 2007 (Yeas 85 Nays 10) and the Senate Floor vote on June 14, 2007 (Yeas 55 Nays 3). Finally, the CTPA became public law - Ley 143 - on July 4, 2007.

The Protocol of Amendment, signed on June 28, 2007, was submitted to the Colombian Congress by, Uribe on July 20 of 2007. The Bill was approved in a joint session on August 29, 2007 and voted by the House Floor on September 25, 2007 (Yeas 84 - Nays 3). After, the Senate Floor approved the Bill on October 30, 2007 (Yeas 54 - Nays 16). Finally, the Protocol of Amendment became public Law - Ley 1116- on November 21, 2007.

The Agreement then underwent a constitutionally mandated court review, according to Colombian regulations. The agreement was deemed to conform to the Colombian Constitution by Colombia's Constitutional Court in July 2008.

Aspects of the agreement relating to copyright are planned to be implemented in Colombia Bill no. 201 of 2012.